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Publications

Event

ESMO Immuno-Oncology (IO) Annual Congress

Geneva, Switzerland | December 2023

  • Discovery of a Novel, Dual CD73 & PD-1 Targeting Multispecific Drug Fc-Conjugate (DFC) for the Treatment of Cancer [Poster] [Abstract]
  • Discovery of CBO421, a First-in-Class Drug Fc-Conjugate (DFC), Targeting CD73 in Cancer [Poster] [Abstract]

Society for Immunotherapy of Cancer (SITC)

San Diego, CA | November 2023

  • Discovery of CBO421, a First-in-Class Drug Fc-conjugate (DFC), Targeting CD73 in Cancer [Poster] [Abstract]

IDWeek

Boston, MA | October 2023

Annual Adenosine-Pathway Targeted Cancer Immunotherapy Summit

Boston, MA | June 2023

International Society for Influenza and Other Respiratory Virus Diseases (ISIRV)

Seattle, WA | May 2023

ESMO Targeted Anticancer Therapies

Paris, France | March 2023

ESWI

Keynote Lecture | December 2020

ESWI

VIRTUAL | December 2020

IDWeek

VIRTUAL | October 2020

IDWeek

Washington, D.C. | October 2019

Manuscript

Keynote Lecture at ESWI | December 2020

Beyond Vaccines and mAbs: Progress Towards Universal Influenza Protection with Cloudbreak® Influenza Antiviral Conjugates (AVCs)

Event

ECCMID

Copenhagen | April 2023

  • All-cause and attributable mortality in invasive candidiasis and/or candidaemia with rezafungin and caspofungin treatment: outcomes from the ReSTORE trial [Presentation] [04732]
  • Safety outcomes with rezafungin and caspofungin in the treatment of candidaemia and/or invasive candidiasis: Phase 3 data from the ReSTORE trial [P2061] [04525]
  • Rezafungin Activity against Candida and Aspergillus Isolates Causing Invasive Infections in European Medical Centres (2019–2021) [P508] [00508]
  • Rezafungin Activity against Candidemia isolates collected from European medical centres (2019–2021) [P509] [00509]
  • Rezafungin and caspofungin treatment response in candidaemia/invasive candidiasis by baseline Candidaspecies: Analysis of pooled Phase 2 and Phase 3 results [P2048] [04353]
  • Treatment outcomes in candidaemia and/or invasive candidiasis among patients receiving rezafungin or caspofungin while the fungal culture was still positive [P2063] [04913]
  • Treatment outcomes with rezafungin and caspofungin in people aged 65 years and above with candidaemia and/or invasive candidiasis: Integrated analysis of pooled Phase 2 and Phase 3 data [03861] [ePoster]
  • First case of Candida glabrata prosthetic knee infection treated with rezafungin: case report [P3398]

IDWEEK

Washington, D.C. – Virtual Hybrid | October 2022

SSAI & ICHS Joint Meeting

Basel, Switzerland | September 2022

ECCMID

Lisbon – Virtual Hybrid | April 2022

EBMT

Virtual | March 2022

TIMM

Virtual | October 2021

IDWeek

Virtual | Sep-Oct 2021

ISICEM

Virtual | August 2021

ISHAM-Asia

Virtual | August 2021

ECCMID

Virtual | July 2021

ICHS SYMPOSIUM

VIRTUAL | February 2021

SCCM

VIRTUAL | January 2021

ESICM LIVES

VIRTUAL | December 2020

IDWeek

VIRTUAL | October 2020

ACCP

VIRTUAL | October 2020

Manuscript

Absence of Clinically Meaningful Drug-Drug Interactions with Rezafungin: Outcome of Investigations | Antimicrobial Chemotherapy | May 2023

Successful expanded access use of rezafungin, a novel echinocandin, to eradicate refractory invasive candidiasis in a liver transplant recipientJ Antimicrob Chemother | Jun 2022

Evaluation of Rezafungin Provisional CLSI Clinical Breakpoints and Epidemiological Cutoff Values Tested against a Worldwide Collection of Contemporaneous Invasive Fungal Isolates (2019 to 2020) | J Clin Microbiol | Apr 2022 | Vol 60, Issue 4

Metabolism, Excretion, and Mass Balance of [14C]-Rezafungin in Animals and Humans | Antimicrob Agents Chemother | January 2022 | Vol 66, Issue 1

Population Pharmacokinetics of Rezafungin in Patients with Fungal Infections | Antimicrob Agents Chemother | October 2021 | Vol 65, Issue 11

The long-acting echinocandin, rezafungin, prevents Pneumocystis pneumonia and eliminates Pneumocystis from the lungs in prophylaxis and murine treatment modelsJ Fungi | September 2021 | Vol 7, Issue 9

Expanded access use of rezafungin for salvage therapy of invasive Candida glabrata infection: A case report | Open Forum Infect Dis | August 2021 | Vol 8, Issue 11

Comparison of In Vitro Killing Activity of Rezafungin, Anidulafungin, Caspofungin, and Micafungin against Four Candida auris Clades in RPMI-1640 in the Absence and Presence of Human Serum | Microorganisms | April 2021 | Vol 9, Issue 4

Efficacy of Rezafungin in Prophylactic Mouse Models of Invasive Candidiasis, Aspergillosis, and Pneumocystis Pneumonia | Antimicrob Agents Chemother | February 2021 | Vol 65, Issue 3

Rezafungin: a novel antifungal for the treatment of invasive candidiasis | Future Microbiol | January 2021 | Vol 16, Issue 1

Rezafungin versus Caspofungin in a Phase 2, Randomized, Double-Blind Study for the Treatment of Candidemia and Invasive Candidiasis – The STRIVE Trial | Clin Infect Dis | September 2020

  • Erratum | Clin Infect Dis | June 2021 | Vol 73, Issue 3

Relative Frequency of Paradoxical Growth and Trailing Effect with Caspofungin, Micafungin, Anidulafungin, and the Novel Echinocandin Rezafungin against Candida SpeciesJ Fungi | August 2020 | Vol 6, Issue 3

Activity of a Long-Acting Echinocandin, Rezafungin, and Comparator Antifungal Agents Tested against Contemporary Invasive Fungal Isolates (SENTRY Program, 2016 to 2018) | Antimicrob Agents Chemother | April 2020 | Vol 64, Issue 4

Rezafungin In Vitro Activity against Contemporary Clinical Nordic Candida Isolates and Candida auris Determined by the EUCAST Reference Method | Antimicrob Agents Chemother | April 2020 | Vol 64, Issue 4

In vitro activity of rezafungin against common and rare Candida species and Saccharomyces cerevisiae | J Antimicrob Chemother | December 2019 | Vol 74, Issue 12

Lack of Effect of Rezafungin on QT/QTc Interval in Healthy Subjects | Clin Pharmacol Drug Dev | December 2019 | Vol 9, Issue 4

Rezafungin Treatment in Mouse Models of Invasive-Candidiasis and Aspergillosis: Insights on the PK/PD Pharmacometrics of Rezafungin Efficacy | Pharmacol Res Perspect | December 2019 | Vol 7, Issue 6

Determination of Pharmacodynamic Target Exposures for Rezafungin against Candida tropicalis and Candida dubliniensis in the Neutropenic Mouse Disseminated Candidiasis Model | Antimicrob Agents Chemother | November 2019 | Vol 63, Issue 11

Extended-Interval Dosing of Rezafungin against Azole-Resistant Aspergillus fumigatusAntimicrob Agents Chemother | October 2019 | Vol 63, Issue 10

Pharmacodynamic Evaluation of Rezafungin (CD101) Against Candida auris in the Neutropenic Mouse Invasive-Candidiasis Model Antimicrob Agents Chemother | November 2018 | Vol 62, Issue 11

Rezafungin (CD101) demonstrates potent in vitro activity against Aspergillus, including azole-resistant Aspergillus fumigatus isolates and cryptic species November 2018 | Vol 73, Issue 11

Rezafungin (CD101), a Next Generation Echinocandin. a Systematic Literature Review and Assessment of Possible Place in Therapy J Glob Antimicrob Resist | September 2018 | Vol 14

EUCAST reference testing of rezafungin susceptibility: impact of choice of plastic plates Antimicrob Agents Chemother | September 2019 | Vol 63, Issue 9

Evaluation of the Efficacy of Rezafungin, a Novel Echinocandin, in the Treatment of Disseminated Candida auris Infection Using an Immunocompromised Mouse Model J Antimicrob Chemother | August 2018 | Vol 73, Issue 8

Population Pharmacokinetic Analyses for Rezafungin (CD101) Efficacy Using Phase 1 Data Antimicrob Agents Chemother | June 2018 | Vol 62, Issue 6

Overcoming the Resistance Hurdle: PK-PD Target Attainment Analyses of Rezafungin (CD101) for Candida albicans and Candida glabrata Antimicrob Agents Chemother | June 2018 | Vol 62, Issue 6

Ex vivo Rezafungin Adsorption and Clearance During Continuous Renal Replacement Therapy Blood Purif | June 2018 | Vol 46, Issue 3

Activity of CD101, a Long-Acting Echinocandin, Against Clinical Isolates of Candida auris Diag Microbiol Infect Dis | March 2018 | Vol 90, Issue 3

Pharmacodynamics of the Long Acting Echinocandin, CD101, in the Neutropenic Invasive-Candidiasis Murine Model Using an Extended-Interval Dosing Design Antimicrob Agents Chemother | February 2018 | Vol 62, Issue 2

CD101, a Novel Echinocandin Possesses Potent Anti -Biofilm Activity Against Early and Mature Candida albicans Biofilms Antimicrob Agents Chemother | February 2018 | Vol 62, Issue 2

The Future of Echinocandin Therapy J Antimicrob Chemother | January 2018 | Vol 73, Issue Suppl 1

In Vitro Potency and Fungicidal Activity of CD101, a Novel Echinocandin, Against Recent Clinical Isolates of Candida Spp. Diag Microbiol Infect Dis | November 2017 | Volume 89, Issue 3

Pharmacological Basis of CD101 Efficacy: Exposure Shape Matters Antimicrob Agents Chemother | November 2017 | Vol 61, Issue 11

Unraveling Drug Penetration of Echinocandin Antifungals at the Site of Infection in an Intra-Abdominal Abscess Model Antimicrob Agents Chemother | October 2017 | Vol 61, Issue 10

CD101, a Long-Acting Echinocandin, and Comparator Antifungal Agents Tested Against a Global Collection of Invasive Fungal Isolates in the SENTRY 2015 Antifungal Surveillance Program Int J Antimicrob Agents | September 2017 | Vol 50, Issue 3

Pharmacokinetics of the Novel Echinocandin, CD101, in Multiple Animal Species Antimicrob Agents Chemother | April 2017 | Volume 61, Issue 4

Activity of a Long-Acting Echinocandin (CD101) and Seven Comparator Antifungal Agents Tested Against a Global Collection of Contemporary Invasive Fungal Isolates in the SENTRY (2014) Antifungal Surveillance Program Antimicrob Agents Chemother | March 2017 | Volume 61, Issue 3

CD101, a Novel Echinocandin With Exceptional Stability Properties and Enhanced Aqueous Solubility J Antibiotics | February 2017 | Volume 70, Issue 2

Structure-Activity Relationships of a Series of Echinocandins and the Discovery of CD101, a Highly Stable and Soluble Echinocandin With Distinctive Pharmacokinetic Properties  Antimicrob Agents Chemother | February 2017 | Volume 61, Issue 2

Safety and Pharmacokinetics of CD101 IV, a Novel Echinocandin, in Healthy Adults  Antimicrob Agents Chemother | February 2017 | Volume 61, Issue 2

Preclinical Evaluation of the Stability, Safety and Efficacy of CD101, a Novel Echinocandin Antimicrob Agents Chemother | November 2016 | Volume 60, Issue 11

Activity of a Long-Acting Echinocandin, CD101, Determined Using CLSI and EUCAST Reference Methods, Against Candida and Aspergillus Spp., Including Echinocandin- and Azole-Resistant Isolates J Antimicrob Chemother | October 2016 | Volume 71, Issue 10

Characterization of in Vitro Resistance Development to the Novel Echinocandin, CD101, in Candida Species Antimicrob Agents Chemother | September 2016 | Volume 60, Issue 10

CD101: a Novel Long-Acting Echinocandin Cell Microbio | September 2016 | Volume 18, Issue 9