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Frequently Asked Questions
Cidara was founded in 2012.
Cidara Therapeutics was co-founded by Kevin Forrest, Ph.D., of 5AM Ventures, Kevin Judice, Ph.D., founder and former chief executive officer of Achaogen Pharmaceuticals, and H. Shaw Warren, M.D., of Harvard University and Massachusetts General Hospital.
The company is headquartered in San Diego, California.
Cidara has assembled a team of senior executives with significant experience in the anti-infective market and a track record of successfully developing and commercializing many anti-infective products. You can view our management team by visiting the “Management Team” section of our website.
Cidara is traded on The NASDAQ Global Market under the symbol “CDTX.” Cidara went public on April 15, 2015.
Cidara is developing therapeutics to improve the standard of care for patients facing serious fungal or viral infections. The Company’s portfolio is comprised of breakthrough approaches aimed at transforming existing treatment and prevention paradigms, first with its lead Phase 3 antifungal candidate, rezafungin, in addition to antiviral conjugates (AVCs) targeting influenza and other viral diseases from Cidara’s proprietary Cloudbreak antiviral platform.
Cidara’s lead product candidate is a novel echinocandin antifungal, rezafungin, intended for the treatment and prevention of life-threatening invasive fungal disease. In addition, Cidara has developed a proprietary immunotherapy platform, Cloudbreak, designed to create compounds that direct a patient’s immune cells to attack and eliminate pathogens that cause infectious disease. Cidara’s lead Cloudbreak compounds target serious viral infections.
The current global market for systemic antifungals is roughly four billion dollars and there is still significant unmet need, with on-treatment mortality rates ranging from 30 to 50 percent for invasive infections. Currently, there are only three classes of antifungals approved to treat and prevent these infections and few antifungals in development. With rising resistance to existing drugs, and given their limitations of toxicity, drug interactions, or once daily IV therapy, the profile of rezafungin will be well-positioned to address patients’ unmet needs.
In May 2015, the U.S. Food and Drug Administration (FDA) designated Cidara’s lead antifungal product candidate, rezafungin, as a Qualified Infectious Disease Product (QIDP) with Fast Track status. The QIDP and Fast Track designation are for the use of rezafungin in the treatment of candidemia and invasive candidiasis. The QIDP designation, provided under the Generating Antibiotic Incentives Now Act (GAIN Act), offers certain incentives for the development of new antibacterial or antifungal drugs, including eligibility for Fast Track, priority review and, if rezafungin is ultimately approved by the FDA, eligibility for an additional five years of marketing exclusivity. You can view the Cidara news announcement for more information.
We often think of fungal infections as simply bothersome conditions such as athlete’s foot or toenail fungus. But certain types of fungal infections, known as “invasive fungal infections” (IFIs), can be dangerous and fatal. IFIs are systemic and are typically caused when fungi invade the body in various ways – such as through the bloodstream or by the inhalation of spores. IFIs can also spread to many other organs – such as the liver and kidney. They are associated with serious illness and death, rising drug resistance and increasing healthcare costs.